Scientific Publications - Eos SENOLYTIX

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Scientific Publications

Predictive Value of [−2]proPSA‐Related Indices for Prostate Cancer Detection Years Before Prostate‐Specific Antigen Elevation: Insights From a Five‐Year Longitudinal Screening Cohort

July 24, 2026

Aged circulating CD8+ T cells and their secreted factors drive cognitive decline

May 23, 2026

Greater lean-body-mass decline with tirzepatide than semaglutide in routine care revealed by body-composition digital phenotyping

April 13, 2026

STIM1-Mitofusin2 interactions tether mitochondria and melanosome contacts that promote melanosome maturation

March 6, 2026

Sustained visceral fat loss is associated with attenuated brain atrophy and improved cognitive function in late midlife

March 4, 2026

Peakspan: Defining, Quantifying and Extending the Boundaries of Peak Productive Lifespan

February 26, 2026

Muscular Strength and Mortality in Women Aged 63 to 99 Years

February 13, 2026

Unintended risks of sarcopenic obesity during weight-loss interventions in older people

February 5, 2026

Muscle-preserving therapies in the era of pharmacological weight loss

January 2, 2026

Comparative analysis of senolytic drugs reveals mitochondrial determinants of efficacy and resistance

December 19, 2025

Two‑phase model of ageing in mice for improved identification of age‑related and late life metabolic decline

October 22, 2025

Metabolic Rewiring Caused by Mitochondrial Dysfunction Promotes mTORC1-Dependent Skeletal Aging

April 18, 2025

Recommendations for Mitochondria Transfer and Transplantation Nomenclature and Characterization

January 16, 2025

Effect of glucagon-like peptide-1 receptor agonists and co-agonists on body composition: Systematic review and network meta-analysis

December 22, 2024

Topical ABT-263 (Navitoclax) Treatment Reduces Aged Skin Senescence and Improves Subsequent Wound Healing

December 3, 2024

Higher skeletal muscle mitochondrial oxidative capacity is associated with preserved brain structure up to over a decade

December 2, 2024

Hepatocellular Senescence Induces Multi-Organ Senescence and Dysfunction via TGF-β

November 13, 2024

Autologous Mitochondrial Transplant for Acute Cerebral Ischemia: Phase 1 Trial Results and Review

November 13, 2024

Blood-derived mitochondrial DNA copy number is associated with Alzheimer disease, Alzheimer-related biomarkers and serum metabolites

October 23, 2024

Inhibition Of IL-11 Signalling Extends Mammalian Healthspan and Lifespan

June 11, 2024

Single Cell and Spatial Transcriptomics Highlight the Interaction of Club-like Cells with Immunosuppressive Myeloid Cells in Prostate Cancer

June 3, 2024

Senescent Cell Transplantation into the Skin Induces Age-Related Peripheral Dysfunction and Cognitive Decline

May 22, 2024

Prevalence of sarcopenic obesity in the older non-hospitalized population: a systematic review and meta-analysis

April 22, 2024

Plasma metabolomic markers underlying skeletal muscle mitochondria function relationships with cognition and motor function

March 12, 2024

Prophylactic and Long-Lasting Efficacy of Senolytic CAR T Cells Against Age-Related Metabolic Dysfunction

January 24, 2024

Inflammatory Biomarkers for Neurobehavioral Dysregulation In Former American Football Players: Findings from the DIAGNOSE CTE Research Project

January 1, 2024

Apoptotic stress causes mtDNA release during senescence and drives the SASP

October 11, 2023

Sarcopenic obesity: epidemiology, pathophysiology, cardiovascular disease, mortality, and management

June 30, 2023

Optogenetic rejuvenation of mitochondrial membrane potential extends C. elegans lifespan

February 28, 2023

Mitochondrial dysfunction in cell senescence and aging

January 1, 2022

Cellular Senescence in Traumatic Brain Injury- Evidence and Perspectives

September 28, 2021

Once-Weekly Semaglutide in Adults with Overweight or Obesity

March 18, 2021

Whole‐Body Senescent Cell Clearance Alleviates Age‐Related Brain Inflammation and Cognitive Impairment In Mice

October 30, 2020

Senolytic CAR T Cells Reverse Senescence – Associated Pathologies

June 17, 2020

The Role of Mitochondria in Neurodegenerative Diseases: the Lesson from Alzheimer’s Disease and Parkinson’s Disease

May 22, 2020

Blast Exposure Leads to Accelerated Senescence in the Rat Brain

May 21, 2020

ECONOMIC IMPACT OF HOSPITALIZATIONS IN US ADULTS WITH SARCOPENIA

April 4, 2019

SA-Beta Gal Following TBI

March 11, 2019

Skeletal Muscle Mass as a Mortality Predictor among Nonagenarians and Centenarians: A Prospective Cohort Study

February 20, 2019

Old Age Increases Microglial Senescence

February 20, 2019

Targeting Senescent Cells Alleviates Obesity‐Induced Metabolic Dysfunction

January 25, 2019

DNA Repair Deficiency and Senescence In Concussed Professional Athletes Involved in Contact Sports

January 1, 2019

Clearance of Senescent Glial Cells Prevents Tau-Dependent Pathology and Cognitive Decline

October 25, 2018

Targeting Cellular Senescence Prevents Age-Related Bone Loss In Mice

September 7, 2017

Transient rapamycin treatment can increase lifespan and healthspan in middle-aged mice

August 23, 2016

Naturally Occurring p16ink4a-Positive Cells Shorten Healthy Lifespan

February 11, 2016

Mitochondria to Motion- Optimizing Oxidative Phosphorylation to Improve Exercise Performance

January 1, 2016

Muscle Mass Index As a Predictor of Longevity in Older Adults

June 1, 2014

p16ink4a Reporter Mice Reveal Age-Promoting Effects of Environmental Toxicants

January 1, 2014

Monitoring Tumorigenesis and Senescence in Vivo With a p16ink4a-Luciferase Model

January 17, 2013

Clearance of p16ink4a-Positive Senescent Cells Delays Ageing-Associated Disorders

November 10, 2011

Reduced Mitochondrial Coupling in vivo Alters Cellular Energetics in Aged Mouse Skeletal Muscle

October 27, 2005

Ageing Oxidative Stress and Mitochondrial Uncoupling

August 24, 2004

A “mitochondrial cascade hypothesis” for sporadic Alzheimer’s Disease

December 2, 2003

Oxidative Capacity and Ageing in Human Muscle

March 24, 2000

A Precursor Form of Prostate-specific Antigen Is More Highly Elevated in Prostate Cancer Compared with Benign Transition Zone Prostate Tissue

February 1, 2000

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