Whole‐Body Senescent Cell Clearance Alleviates Age‐Related Brain Inflammation and Cognitive Impairment In Mice

Diet: naturally aged mice on a high-fat diet.
From 80 weeks of age: PTC-2105 (25 mg/kg, 3×/week), semaglutide ("SMG") or saline.
Dosing stopped: semaglutide ("SMG") at study week 35; PTC-2105 and saline at week 45.
Today: Gordito is still alive, around 40 weeks after his last dose of PTC-2105.

By egalliOctober 30, 2020February 17th, 2026No Comments